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Fluorescence SIM available at EMSL

A new super resolution fluorescence structured illumination microscopy system, or fluorescence SIM, is now available at EMSL as part of the lab’s Cell Isolation and Systems Analysis capabilities. Access to the new instrument is through EMSL’s user proposal process. The EMSL Usage System lists it as Microscope: Fluorescence, Super Resolution Structured Illumination.

Classified as a super resolution microscope, the fluorescence SIM delivers significantly higher spatial resolution imaging than conventional light microscopes. The fluorescence SIM’s resolving power is about 100-130 nanometers. Light microscopes cannot resolve structures smaller than approximately 250-300 nanometers. To put that into perspective, a water molecule is less than one nanometer, and a typical germ is about 1,000 nanometers.

Read more on the EMSL website

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